Salivary PYY: A Putative Bypass to Satiety

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Salivary PYY: A Putative Bypass to Satiety

Peptide YY(3-36) is a satiation hormone released postprandially into the bloodstream from L-endocrine cells in the gut epithelia. In the current report, we demonstrate PYY(3-36) is also present in murine as well as in human saliva. In mice, salivary PYY(3-36) derives from plasma and is also synthesized in the taste cells in taste buds of the tongue. Moreover, the cognate receptor Y2R is abundan...

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When gut fermentation controls satiety: A PYY story

Gut microbiota is now considered to be an important regulator of body weight. With approximately 10 million genes [1], the gut metagenome is certainly hiding numerous mechanisms involved in the control of body weight and the consequent metabolic disease [2]. Among them, bacterial enzymes fermenting non-digestible dietary fibers into the short chain fatty acids (SCFA) acetate, propionate, and bu...

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Fermentable carbohydrate stimulates FFAR2-dependent colonic PYY cell expansion to increase satiety

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Satiety, but not total PYY, is increased with continuous and intermittent exercise

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ژورنال

عنوان ژورنال: PLoS ONE

سال: 2011

ISSN: 1932-6203

DOI: 10.1371/journal.pone.0026137